Kimura disease of Submandibular Lymph Node: A Case Report and Review of Literature
Kimura Disease (KD) is a rare benign chronic inflammatory disorder, believed to be resulted from an immune-mediated hypersensitivity reaction to unknown agents. Clinically, it usually manifests as painless subcutaneous nodules in the head or neck region, accompanied by regional lymphadenopathy or salivary gland involvement. Laboratory finding shows peripheral blood and tissue eosinophilia, together with markedly elevated serum immunoglobulin E (IgE) levels. KD is often confused with angiolymphoid hyperplasia with eosinophilia (ALHE), another separate entity with overlapping histopathologic features. A case of KD in a 30-year-old Thai male with right submandibular swelling was presented together with a brief review of literature.
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