Assessment of Dental Pulp Volumes of Maxillary Permanent Teeth in Thai Patients with Complete Unilateral Cleft Lip and Palate using Cone Beam Computed Tomography
Objectives: To assess and compare the dental pulp volumes of the maxillary permanent teeth between the cleft and the non-cleft sides in Thai patients with complete unilateral cleft lip and palate (UCLP), using cone beam computed tomography.
Materials and Methods: Two hundred and eight CBCT images of maxillary permanent teeth of 20 Thai patients with complete UCLP (mean age 10.50 ± 2.24 years) were used to construct three-dimensional dental pulp models. The dental pulp volume of each tooth was calculated automatically by Mimics Research 15.01 software. The mean dental pulp volume of each tooth type from both sides was compared, using the parametric paired sample t-test (p < 0.05).
Results: The maxillary first molar illustrated the greatest dental pulp volume (96.16±25.93 mm3 on the cleft side and 95.99±29.17 mm3 on the non-cleft side), and the maxillary lateral incisor presented the least (17.50±9.76 mm3 on the cleft side and 26.62±11.96 mm3 on the non-cleft side). The comparisons of the dental pulp volumes of the maxillary permanent teeth on the cleft side and those of their counterparts on the non-cleft side revealed no significant differences.
Conclusions: The dental pulp volume of maxillary permanent teeth in Thai patients with complete UCLP did not associate with the CLP anomaly. The maxillary first molar showed the greatest dental pulp volume while the maxillary lateral incisor showed the least.
1. Dixon MJ, Marazita ML, Beaty TH, Murray JC. Cleft lip and palate: understanding genetic and environmental influences. Nat Rev Genet 2011; 12(3): 167-178.
2. Ribeiro LL, Neves LTD, Costa B, Gomide MR. Dental development of permanent lateral incisor in complete unilateral cleft lip and palate. Cleft Palate Craniofac J 2002; 39(2): 193-196.
3. Celikoglu M, Buyuk S, Sekerci A, Cantekin K, Candirli C. Maxillary dental anomalies in patients with cleft lip and palate: a cone beam computed tomography study. J Clin Pediatr Dent 2015; 39(2): 183-186.
4. Haque S, Alam MK. Common dental anomalies in cleft lip and palate patients. Malays J Med Sci 2015; 22(2): 55-60.
5. Lehtonen V, Anttonen V, Ylikontiola L, Koskinen S, Pesonen P, Sándor G. Dental anomalies associated with cleft lip and palate in Northern Finland. Eur J Paediatr Dent 2015; 16(4): 327-332.
6. Rullo R, Festa V, Rullo R, et al. Prevalence of dental anomalies in children with cleft lip and unilateral and bilateral cleft lip and palate. Eur J Paediatr Dent 2015; 16(3): 229-232.
7. Amarlal D, Muthu M, Kumar NS. Root development of permanent lateral incisor in cleft lip and palate children: a radiographic study. Indian J Dent Res 2007; 18(2): 82-86.
8. Brouwers HJ, Kuijpers AM. Development of permanent tooth length in patients with unilateral cleft lip and palate. Am J Orthod Dentofacial Orthop 1991; 99(6): 543-549.
9. Ranta R. A review of tooth formation in children with cleft lip/palate. Am J Orthod Dentofacial Orthop 1986; 90(1): 11-18.
10. Celebi AA, Ucar FI, Sekerci AE, Caglaroglu M, Tan E. Effects of cleft lip and palate on the development of permanent upper central incisors: a cone-beam computed tomography study. Eur J Orthod 2014; 37(5): 544-549.
11. Lai MC, King NM, Wong HM. Dental development of Chinese children with cleft lip and palate. Cleft Palate Craniofac J 2008; 45(3): 289-296.
12. Cohnen M, Kemper J, Mobes O, Pawelzik J, Modder U. Radiation dose in dental radiology. Eur Radiol 2002; 12(3): 634-637.
13. Terlemez A, Alan R, Gezgin O. Evaluation of the Periodontal Disease Effect on Pulp Volume. J Endod 2018; 44(1): 111-114.
14. Javed F, Al-Kheraif AA, Romanos EB, Romanos GE. Influence of orthodontic forces on human dental pulp: a systematic review. Arch Oral Biol 2015; 60(2): 347-356.
15. Venkatesh S, Ajmera S, Ganeshkar SV. Volumetric pulp changes after orthodontic treatment determined by cone-beam computed tomography. J Endod 2014; 40(11): 1758-1763.
16. Ge ZP, Ma RH, Li G, Zhang JZ, Ma XC. Age estimation based on pulp chamber volume of first molars from cone-beam computed tomography images. Forensic Sci Int 2015; 253: 133.e1-7.
17. Ge ZP, Yang P, Li G, Zhang JZ, Ma XC. Age estimation based on pulp cavity/chamber volume of 13 types of tooth from cone beam computed tomography images. Int J Legal Med 2016; 130(4): 1159-1167.
18. Star H, Thevissen P, Jacobs R, Fieuws S, Solheim T, Willems G. Human dental age estimation by calculation of pulp-tooth volume ratios yielded on clinically acquired cone beam computed tomography images of monoradicular teeth. J Forensic Sci 2011; 56(Suppl 1): S77-82.
19. Tardivo D, Sastre J, Ruquet M, et al. Three-dimensional modeling of the various volumes of canines to determine age and sex: a preliminary study. J Forensic Sci 2011; 56(3): 766-770.
20. Yang F, Jacobs R, Willems G. Dental age estimation through volume matching of teeth imaged by cone-beam CT. Forensic Sci Int 2006; 159(Suppl 1): S78-83.
21. Fanibunda KB. A method of measuring the volume of human dental pulp cavities. Int Endod J 1986; 19(4): 194-197.
22. Fisher DE, Ingersoll N, Bucher JF. Anatomy of the pulpal canal: three-dimensional visualization. J Endod 1975; 1(1): 22-25.
23. Barker BC, Parsons KC, Mills PR, Williams GL. Anatomy of root canals. I. Permanent incisors, canines and premolars. Aust Dent J 1973; 18(5): 320-327.
24. Gulsahi A, Kulah CK, Bakirarar B, Gulen O, Kamburoglu K. Age estimation based on pulp/tooth volume ratio measured on cone-beam CT images. Dentomaxillofac Radiol 2018; 47(1): 20170239.
25. Asif MK, Nambiar P, Mani SA, Ibrahim NB, Khan IM, Lokman NB. Dental age estimation in Malaysian adults based on volumetric analysis of pulp/tooth ratio using CBCT data. Leg Med (Tokyo) 2019; 36: 50-58.
26. Danforth RA, Clark DE. Effective dose from radiation absorbed during a panoramic examination with a new generation machine. Oral Surg Oral Med Oral Pathol Oral Radiol Endod 2000; 89(2): 236-243.
27. Gibbs SJ. Effective dose equivalent and effective dose: comparison for common projections in oral and maxillofacial radiology. Oral Surg Oral Med Oral Pathol Oral Radiol Endod 2000; 90(4): 538-545.
28. Ngan D, Kharbanda OP, Geenty JP, Darendeliler M. Comparison of radiation levels from computed tomography and conventional dental radiographs. Aust Orthod J 2003; 19(2): 67-75.