Desmoplastic Ameloblastoma: A Report of Two Cases

Among the ameloblastomas, the desmoplastic variation is a rare variant that accounts for approximately 4–13 %. The desmoplastic ameloblastoma displays significant differences in anatomical sites, radiographic features and histologic appearances from the other ameloblastoma subtypes. We here present two patients with desmoplastic ameloblastomas in the maxilla and the mandible. Clinically, both patients presented with painless swelling of the jaw bone. An ill-defined, mixed radiolucent-radiopaque appearance was evident on panoramic radiographs. The definitive diagnosis of desmoplastic ameloblastomas were achieved by incisional biopsies. Subsequently, partial resection of the maxilla or the mandible were performed. The patients are on routine follow-up. No sign of recurrence was observed.

Belgaumi UI, Sundaresh KJ, Varma S, Mallikarjuna R. Desmoplastic ameloblastoma: a rare odontogenic neoplasm with unusual radiographic and histomorphological presentation. BMJ Case Reports [serial on the internet] 2013 May [cited 2017 Oct 20][about 4 p.]. Available from: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC36700...

Gade L, Patankar S, Khot K, Korde S, Alex S. Desmoplastic ameloblastoma of maxilla-a case report. J Clin Exp Dent 2010;2(4):e204-6.

Kaffe I, Buchner A, Taicher S. Radiologic features of desmoplastic variant of ameloblastoma. Oral Surg Oral Med Oral Pathol 1993;76:525–9.

Sun ZJ, Wu YR, Cheng N, Zwahlen RA, Zhao YF. Desmoplastic ameloblastoma—a review. Oral Oncol 2009;45:752–9.

Kawai T, Kishino M, Hiranuma H, Sasai T, Ishida T. A unique case of desmoplastic ameloblastoma of the mandible: report of a case and brief review of the English language literature. Oral Surg Oral Med Oral Pathol Oral Radiol Endod 1999; 87: 258–63.

Takata T, Miyauchi M, Ito H, et al. Clinical and Histopathological Analyses of Desmoplastic Ameloblastoma. Pathol Res Pract 1999; 95:669-75.

Fujimura M, Sato T, Kawano K, Morita Y, Noikura T, Yamashita S. Two cases of ameloblastoma with an unusual radiographic appearance. Dent Radiol 1987;27:154–60.

Masao A, Naoyuki M, Kazuya H, et al. Ameloblastoma, desmoplastic type: a case report with characteristic radiological presentation. Oral Radiol 2012;28:70–3.

Kallam SR, Arutla R, Gadwalwari SS, Kubbi JR, Shylaja SR. Desmoplastic Ameloblastoma – An Unusual Presentation. J Clin Diagn Res [serial on the internet] 2015 Oct [cited 2017 Oct 20]; 9(10):[about 2 p]. Available from:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC46253...

Barnes L, Eveson JW, Reichart P, Sidransky D. World Health Organization classifications of tumours. Pathology and Genetics of Head and Neck Tumours. Lyon: IARC; 2005:300-1.

Waldron CA, El Mofty SK. A histopathologic study of 116 ameloblastomas with special reference to the desmoplastic variant. Oral Surg Oral Med Oral Pathol 1987;63:441–51.

Marx R, Carlson E. The ameloblastoma: primary, curative surgical management. J Oral Maxillofac Surg 2006;64:484–94.

Reichart PA, Philipsen HP, Sonner S. Ameloblastoma: biological profile of 3677 cases. Eur J Cancer B Oral Oncol 1995;31:86–99.

Philipsen HP, Reichart PA. Revision of the 1992-edition of the WHO histological typing of odontogenic tumours. A suggestion. J Oral Pathol Med 2002,31:253–8.

Sheikh S, Pallagatti S, Singla I, Kalucha A. Desmoplastic Ameloblastoma: A Case Report. J Dent Res Dent Clinic Dent Prospects 2011;5(1):27-32.

Sharma Lamichhane N, Liu Q, Sun H, Zhang W. A case report on desmoplastic ameloblastoma of anterior mandible. BMC research notes 2016;9:171.

Friman T. Extracellular Matrix and Connective Tissue Cells of the Tumor Microenvironment. Digital Comprehensive Summaries of Uppsala Dissertation from the Faculty of Medicine 613. 2010;37.

Konchanthes S, Chamusi N. Desmoplastic Ameloblastoma: A Report of Two Cases: A case reports/series. CM Dent J [Internet]. 2018 Feb 14 [cited 2024 Nov 18];39(1):127-136. Available from: https://www.dent.cmu.ac.th/cmdj/frontend/web/?r=site/viewarticle&id=134

Konchanthes, S. & Chamusi, N. (2018). Desmoplastic Ameloblastoma: A Report of Two Cases. CM Dent J, 39(1), 127-136. Retrieved from: https://www.dent.cmu.ac.th/cmdj/frontend/web/?r=site/viewarticle&id=134

Konchanthes, S., and Chamusi Nutchapon. 2018. "Desmoplastic Ameloblastoma: A Report of Two Cases." CM Dent J, 39(1), 127-136. https://www.dent.cmu.ac.th/cmdj/frontend/web/?r=site/viewarticle&id=134

Konchanthes, S. et al. 2018. 'Desmoplastic Ameloblastoma: A Report of Two Cases', CM Dent J, 39(1), 127-136. Retrieved from https://www.dent.cmu.ac.th/cmdj/frontend/web/?r=site/viewarticle&id=134

Konchanthes, S. and Chamusi, N. "Desmoplastic Ameloblastoma: A Report of Two Cases", CM Dent J, vol.39, no. 1, pp. 127-136, Feb. 2018.

Konchanthes Sasithorn, Chamusi Nutchapon "Desmoplastic Ameloblastoma: A Report of Two Cases." CM Dent J, vol.39, no. 1, Feb. 2018, pp. 127-136, https://www.dent.cmu.ac.th/cmdj/frontend/web/?r=site/viewarticle&id=134